About the project


Description of the LD-Portal:

Mejhert N, Gabriel KR, et al.
The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology.
Submitted for publication, 2021.
bioRxiv preprint

Results on RNAi screening, RNA-seq, and proteomics in THP-1 and SUM159 cells:

Mejhert N et al.
Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression.
Mol Cell. 2020 Mar 19;77(6):1251-1264.e9. doi: 10.1016/j.molcel.2020.01.014.
PMID: 32023484

Results on mouse liver proteomics and phosphoproteomics:

Krahmer N et al.
Organellar Proteomics and Phospho-Proteomics Reveal Subcellular Reorganization in Diet-Induced Hepatic Steatosis.
Dev Cell. 2018 Oct 22;47(2):205-221.e7. doi: 10.1016/j.devcel.2018.09.017.
PMID: 30352176

Multi-marker Analysis of GenoMic Annotation (MAGMA) method:

de Leeuw C et al.
MAGMA: generalized gene-set analysis of GWAS data.
PLoS Comput Biol. 2015 Apr 17;11(4):e1004219. doi: 10.1371/journal.pcbi.1004219..
PMID: 25885710

MAGMA software

Knowledge Portal Team

Project directors Noël Burtt
Jason Flannick
Creative lead Maria Costanzo
Software engineers Marc Duby
Clint Gilbert
Quy Hoang
Dong-Keun Jang
Jeffrey Massung
Oliver Ruebenacker
Preeti Singh
Computational biologist Ryan Koesterer
Project manager Lizz Caulkins

Contact the team to make suggestions or get individual help.